Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316954 | 0.89 | POLB (0.44) | DRD2HTR1AALDH1A1LMNAKDM4E | |
| SCHEMBL5317594 | 0.89 | HTR1A (0.40) | DRD2HTR1AALDH1A1KDM4EKMT2A | |
| SCHEMBL5314840 | 0.87 | HTR1A (0.53) | DRD2HTR1AALDH1A1KDM4EKMT2A | |
| SCHEMBL5315934 | 0.87 | MCHR1 (0.48) | DRD2HTR1AALDH1A1LMNAKDM4E | |
| SCHEMBL5331515 | 0.85 | LMNA (0.50) | DRD2HTR1AALDH1A1LMNAMEN1 | |
| SCHEMBL5319733 | 0.85 | POLB (0.48) | DRD2HTR1AALDH1A1KDM4EKMT2A | |
| SCHEMBL5316681 | 0.84 | POLB (0.40) | DRD2HTR1AALDH1A1KDM4EPOLB | |
| SCHEMBL5316192 | 0.83 | HTT (0.52) | DRD2HTR1AALDH1A1KDM4EMEN1 | |
| SCHEMBL5314874 | 0.83 | POLB (0.54) | DRD2HTR1AALDH1A1LMNAKDM4E | |
| SCHEMBL5317453 | 0.82 | KMT2A (0.48) | DRD2HTR1AALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |