SCHEMBL531886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5350350	1.00	ALDH5A1 (0.48)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL531788	0.90	ALDH1A1 (0.49)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL15331980	0.87	ALDH5A1 (0.48)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL531831	0.87	ALDH5A1 (0.50)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL2559542	0.86	GRIN2D (0.49)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL531627	0.84	ALDH1A1 (0.46)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL29951075	0.83	SMN1; SMN2 (0.50)	ALDH5A1ABATALDH1A1LMNACYP1A2
	SCHEMBL12992431	0.83	TTR (0.50)	ALDH1A1LMNAMAPTHPGDTTR
	SCHEMBL30806568	0.83	ALDH1A1 (0.53)	ALDH1A1LMNAMAPTHPGDHTT
	SCHEMBL28918509	0.82	ALDH5A1 (0.50)	ALDH5A1ABATALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.