Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182187 | 0.68 | MAP4K4 (0.32) | KMT2A | |
| SCHEMBL8906502 | 0.67 | HCAR3 (0.53) | HSD17B10AGTR1AGTR2HCAR3HSP90AA1 | |
| SCHEMBL5316682 | 0.66 | HSD17B10 (0.44) | HSD17B10HTTAGTR1AGTR2SMN1; SMN2 | |
| SCHEMBL186575 | 0.66 | NPC1 (0.41) | RXRAL3MBTL1KMT2A | |
| SCHEMBL136422 | 0.66 | ALDH1A1 (0.46) | HSD17B10L3MBTL1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL16246829 | 0.65 | L3MBTL1 (0.40) | L3MBTL1 | |
| SCHEMBL4890597 | 0.64 | MAP4K4 (0.36) | SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL619635 | 0.64 | — | — | |
| SCHEMBL5004570 | 0.64 | KDM4E (0.31) | L3MBTL1KDM4EKMT2A | |
| SCHEMBL8522823 | 0.63 | RARG (0.37) | HSD17B10RXRAL3MBTL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |