Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317600 | 0.81 | LMNA (0.47) | HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL8906502 | 0.73 | HCAR3 (0.53) | HSD17B10HPGDTHRBAGTR1AGTR2 | |
| SCHEMBL5317401 | 0.71 | HSD17B10 (0.73) | HSD17B10HTTSMN1; SMN2HPGDTHRB | |
| SCHEMBL1357578 | 0.71 | PPARG (0.46) | HSD17B10THRBAGTR1AGTR2 | |
| SCHEMBL8396137 | 0.69 | HSD17B10 (0.47) | HSD17B10AGTR1AGTR2 | |
| SCHEMBL22160864 | 0.68 | HSD17B10 (0.51) | HSD17B10HTTSMN1; SMN2HPGDTHRB | |
| SCHEMBL619634 | 0.68 | MAPK1 (0.78) | SMN1; SMN2HPGDATM | |
| SCHEMBL4256918 | 0.68 | THRB (0.77) | HSD17B10HTTSMN1; SMN2HPGDTHRB | |
| SCHEMBL5782481 | 0.67 | HSD17B10 (0.47) | HSD17B10HTTSMN1; SMN2HPGDTHRB | |
| SCHEMBL5520760 | 0.67 | TP53 (0.51) | HSD17B10HTTSMN1; SMN2CRBNAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |