Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873808 | 0.82 | PGR (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL9956677 | 0.81 | PGR (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL10194676 | 0.80 | CCNK (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL30204212 | 0.78 | ROCK2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL2578635 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL6170106 | 0.78 | KMT2A (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL22312043 | 0.77 | KMT2A (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4PGR | |
| SCHEMBL6631039 | 0.75 | ALDH1A1 (0.55) | KMT2AALDH1A1LMNAMAPTTSHR | |
| SCHEMBL9263725 | 0.75 | APP (0.42) | KMT2ACA2CA1PDK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29472307 | 0.75 | KMT2A (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |