Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318523 | 0.92 | HTR1A (0.43) | POLBCCR5HTR1ADRD2HTR7 | |
| SCHEMBL5318113 | 0.91 | POLB (0.53) | POLBHTR1ADRD2HTR7HTR6 | |
| SCHEMBL5314574 | 0.90 | KCNH2 (0.43) | POLBCCR5HTR1ADRD2HTR7 | |
| SCHEMBL5316850 | 0.90 | HTR1A (0.49) | POLBHTR1ADRD2HTR7HTR6 | |
| SCHEMBL5319026 | 0.90 | HTR1A (0.49) | POLBHTR1ADRD2HTR7HTR6 | |
| SCHEMBL5316269 | 0.90 | HTR1A (0.45) | POLBHTR1ADRD2HTR7HTR6 | |
| SCHEMBL5315933 | 0.85 | HTR1A (0.47) | POLBCCR5HTR1ADRD2HTR7 | |
| SCHEMBL5316192 | 0.81 | HTT (0.52) | POLBHTR1ADRD2HTR7HTR6 | |
| SCHEMBL5314874 | 0.81 | POLB (0.54) | POLBHTR1ADRD2HTR7HTR6 | |
| SCHEMBL5315867 | 0.81 | ERCC1 (0.44) | POLBDRD2KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |