SCHEMBL5317688

SCHEMBL5317688

COC(C)OC(C)OC(OC(=O)c1ccccn1)(OC(C)OC(C)OC)OC(C)OC(C)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
PKM P14618 3/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
HTT P42858 1/20 0.40
LMNA P02545 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GSK3B P49841 1/20 0.39
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 1/20 0.38
ALPL P05186 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5311142 0.84 PKM (0.39) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL5312198 0.78 CYP1A2 (0.43) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL5315941 0.76 LMNA (0.42) KDM4EMAPTPOLBALDH1A1LMNA
SCHEMBL4349768 0.74 PKM (0.47) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL29550139 0.73 ALDH1A1 (0.55) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL2652708 0.73 ALDH1A1 (0.55) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL3912008 0.72 APP (0.46) KDM4EMAPTPOLBALDH1A1KMT2A
Fluoride SCHEMBL28087422 0.71 ALDH1A1 (0.53) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL29576494 0.70 KDM4E (0.68) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL30166417 0.70 KDM4E (0.68) KDM4EMAPTPOLBALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed