SCHEMBL5317814

SCHEMBL5317814

NNCCc1c[nH]c2ccccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.70
ALDH1A1 P00352 2/20 0.70
KDM4E B2RXH2 1/20 0.70
HTR1A P08908 1/20 0.70
HTT P42858 1/20 0.70
MC5R P33032 1/20 0.68
MC3R P41968 1/20 0.68
MC1R Q01726 1/20 0.68
CYP1A2 P05177 2/20 0.66
CYP3A4 P08684 2/20 0.66
MPO P05164 1/20 0.66
CYP2D6 P10635 1/20 0.66
CYP2A6 P11509 1/20 0.66
NFKB1 P19838 1/20 0.66
HTR1D P28221 1/20 0.66
HTR1B P28222 1/20 0.66
HTR2C P28335 1/20 0.66
HTR7 P34969 1/20 0.66
CTSK P43235 1/20 0.66
HTR6 P50406 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17232881 0.85 MC5R (0.83) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL7970552 0.84 MC5R (0.81) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL4985934 0.82 HTR2A (0.77) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL379409 0.82 HTR2A (1.00) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL4428860 0.82 HTR2A (0.70) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL106450 0.82 HTR2A (0.70) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL3377341 0.82 HTR2A (0.70) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL29385251 0.82 HTR2A (1.00) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL3377723 0.82 HTR2A (0.70) HTR2AALDH1A1KDM4EHTR1AHTT
SCHEMBL10089577 0.82 HTR2A (0.70) HTR2AALDH1A1KDM4EHTR1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137730-A1 N-SUBSTITUTED TRYPTAMINES AND N-SUBSTITUTED LYSERGAMIDES AND THEIR USE AS THERAPEUTIC AGENTS ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) 2025-06-26 WO disclosed
US-20240417764-A1 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY 2024-12-19 US disclosed
EP-4426676-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-09-11 EP disclosed
US-20240189331-A1 NOVEL TRYPTAMINE ORAL FILM FORMULATION INTELGENX CORP. (CA) 2024-06-13 US disclosed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 WO disclosed
US-11905295-B2 Solid forms of tabernanthalog monofumarate salt for treating neurological disorders and/or psychiatric disorders TERRAN BIOSCIENCES INC. (US) 2024-02-20 US disclosed
US-20230279017-A1 SALT AND SOLID FORMS OF TABERNANTHALOG TERRAN BIOSCIENCES INC. 2023-09-07 US disclosed
US-20230257385-A1 SALT AND SOLID FORMS OF TABERNANTHALOG TERRAN BIOSCIENCES INC (US) 2023-08-17 US disclosed
WO-2023092045-A1 SALT AND SOLID FORMS OF TABERNANTHALOG TERRAN BIOSCIENCES, INC. (US) 2023-05-25 WO disclosed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 WO disclosed
WO-2009123986-A1 APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-10-08 WO disclosed
WO-2007077457-A9 TREATMENT OF EQUINE LAMINITIS WITH 5-HT1B/ 1D ANTAGONISTS ROYAL VETERINARY COLLEGE (GB) 2007-10-18 WO disclosed
CN-101049485-A Mulberry - ginger soft capsule for treating common cold, and preparation method HE ZUXIN (CN) 2007-10-10 CN disclosed
CN-1898201-A Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents SENTION INC (US) 2007-01-17 CN disclosed
CN-1610547-A N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor LILLY CO ELI (US) 2005-04-27 CN disclosed
US-20030059797-A1 Animal model of and test for Alzheimer's disease PALEY ELENA (US) 2003-03-27 US disclosed
US-5798337-A USED TO PROMOTE GROWTH IN MAMMALS EITHER ALONE OR IN COMBINATION WITH OTHER GROWTH PROMOTING COMPOUNDS GENENTECH, INC. (US) 1998-08-25 US disclosed
US-5220016-A Condensing a Grignard reagent of a protected piperidinylmethanol with a protected 2-methoxyoxalylindole; coupling with vidoline;deprotecting and cyclicizing BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-06-15 US disclosed
US-4229463-A ANTICHOLESTEROL AGENTS FOR REDUCING CHOLESTEROL ESTER CONTENT OF ARTERIAL WALLS SANDOZ, INC. (US) 1980-10-21 US disclosed
US-4201785-A ANTICHOLESTEROL AGENTS SANDOZ INC. (US) 1980-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257385-A1 SALT AND SOLID FORMS OF TABERNANTHALOG SLC6A2, SLC6A4, SLC6A3 HTR2A 794/4885ALDH1A1 759/4885KDM4E 3806/4885
US-20240189331-A1 NOVEL TRYPTAMINE ORAL FILM FORMULATION TPH2, TPH1, HTR2A HTR2A 3/4885ALDH1A1 3809/4885KDM4E 1171/4885
US-20230279017-A1 SALT AND SOLID FORMS OF TABERNANTHALOG SLC6A2, SLC6A4, SLC6A3 HTR2A 794/4885ALDH1A1 759/4885KDM4E 3806/4885
US-11905295-B2 Solid forms of tabernanthalog monofumarate salt for treating neurological disorders and/or psychiatric disorders FAH, SLC6A3, SLC6A2 HTR2A 736/4885ALDH1A1 677/4885KDM4E 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.