Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 0.55 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.45 |
| ▸ | FLT1 | P17948 | 5/20 | 0.43 |
| ▸ | FLT4 | P35916 | 5/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316742 | 0.78 | SIRT7 (0.60) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5316767 | 0.74 | VCP (0.60) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5343891 | 0.74 | VCP (0.58) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5338652 | 0.74 | VCP (0.58) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5316983 | 0.74 | VCP (0.58) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5316977 | 0.73 | VCP (0.55) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5319635 | 0.73 | VCP (0.52) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5319878 | 0.73 | FLT1 (0.76) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5319128 | 0.72 | VCP (0.51) | VCPSIRT7IMPDH2FLT1FLT4 | |
| SCHEMBL5318214 | 0.72 | PIK3CG (0.62) | VCPSIRT7KDM4EPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |