Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.52 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316833 | 0.89 | IMPDH2 (0.54) | VCPLMNANPSR1ALOX15MAPK1 | |
| SCHEMBL5316977 | 0.84 | VCP (0.55) | VCPSIRT7IMPDH2PIK3CGALOX5 | |
| SCHEMBL5318214 | 0.80 | PIK3CG (0.62) | VCPSIRT7HSD17B10NPC1ALDH1A1 | |
| SCHEMBL5316983 | 0.78 | VCP (0.58) | VCPSIRT7NPC1MEN1KMT2A | |
| SCHEMBL5318254 | 0.73 | VCP (0.58) | VCPSIRT7IMPDH2PIK3CGFLT1 | |
| SCHEMBL5316742 | 0.73 | SIRT7 (0.60) | VCPSIRT7NPC1RAB9AHTT | |
| SCHEMBL5318096 | 0.73 | VCP (0.55) | VCPSIRT7KDM4EIMPDH2PIK3CG | |
| SCHEMBL5319609 | 0.73 | VCP (0.55) | VCPSIRT7IMPDH2PIK3CGFLT1 | |
| SCHEMBL5320437 | 0.73 | IMPDH2 (0.57) | VCPIMPDH2FLT1FLT4KDR | |
| SCHEMBL5316767 | 0.72 | VCP (0.60) | VCPSIRT7IMPDH2ALOX5FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |