Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 3/20 | 0.58 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 8/20 | 0.45 |
| ▸ | FLT1 | P17948 | 7/20 | 0.45 |
| ▸ | FLT4 | P35916 | 7/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318254 | 0.91 | VCP (0.58) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL14466975 | 0.88 | KDR (0.60) | VCPKDRFLT1FLT4IMPDH2 | |
| SCHEMBL5316977 | 0.81 | VCP (0.55) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL5319793 | 0.78 | IMPDH2 (0.60) | VCPKDRFLT1FLT4IMPDH2 | |
| SCHEMBL5319635 | 0.78 | VCP (0.52) | VCPSIRT7MEN1NPC1RAB9A | |
| SCHEMBL5316767 | 0.77 | VCP (0.60) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL5316742 | 0.76 | SIRT7 (0.60) | VCPSIRT7NPC1RAB9AKDR | |
| SCHEMBL5319609 | 0.76 | VCP (0.55) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL5318214 | 0.75 | PIK3CG (0.62) | VCPSIRT7NPC1RAB9ADYRK1A | |
| SCHEMBL15121062 | 0.74 | KDR (0.47) | VCPSIRT7MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |