Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827282 | 0.72 | MAPT (0.59) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL11827286 | 0.72 | MAPT (0.59) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL43431 | 0.72 | CES2 (0.40) | BCHENPSR1CES2CES1 | |
| SCHEMBL28343398 | 0.70 | NFKB1 (0.68) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL30673968 | 0.70 | NFKB1 (0.68) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL5926594 | 0.69 | MAPT (0.50) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL5318170 | 0.68 | NFKB1 (0.45) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL336239 | 0.68 | MMP1 (0.52) | NFE2L2CA1CA2MAOBMAPT | |
| SCHEMBL336240 | 0.68 | MMP1 (0.52) | NFE2L2CA1CA2MAOBMAPT | |
| SCHEMBL5312917 | 0.68 | NFKB1 (0.47) | NFKB1JUNNFE2L2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803809-A2 | Modulation of peroxisome proliferator-activated receptors | Abgenomics Corporation (TW) | 2007-07-04 | — | — | EP | disclosed |
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | ABGENOMICS CORPORATION (TW) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | PPARG, PPARA, PPARD | NFKB1 1541/4885JUN 2187/4885NFE2L2 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.