SCHEMBL43431

SCHEMBL43431

[N-]=[N+]=CC(=O)OC(F)c1cccc(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.40
CES1 P23141 3/20 0.40
BCHE P06276 1/20 0.34
NPSR1 Q6W5P4 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
GLS O94925 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43500 0.78
SCHEMBL5318174 0.72 NFKB1 (0.44) CES2CES1BCHENPSR1
SCHEMBL4606754 0.68 CES2 (0.40) CES2CES1
SCHEMBL8720874 0.67 CES2 (0.55) CES2CES1BCHENPSR1
SCHEMBL4418499 0.64 CES2 (0.51) CES2CES1BCHEGLS
Hydrochloric Acid SCHEMBL8873978 0.64 IDO1 (0.46) CES2CES1BCHE
SCHEMBL27876509 0.64 CES2 (0.47) CES2CES1BCHENPSR1GLS
SCHEMBL27700199 0.63 CES2 (0.46) CES2CES1BCHE
SCHEMBL6405941 0.63 CES2 (0.44) CES2CES1BCHEGLS
SCHEMBL7777116 0.63 CES2 (0.53) CES2CES1BCHENPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011157444-A1 FUNCTIONALIZED MATERIALS BY CATALYZED CARBENE COPOLYMERIZATION STICHTING DUTCH POLYMER INSTITUTE (NL) 2011-12-22 WO disclosed