Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 7/20 | 0.52 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3641914 | 0.90 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2NAMPTPOLB | |
| SCHEMBL5277311 | 0.90 | TAS1R3 (0.63) | TAS1R3TAS1R1TAS1R2NAMPTPOLB | |
| SCHEMBL5278123 | 0.88 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2NAMPTPOLB | |
| SCHEMBL5923954 | 0.82 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2NAMPTRAB9A | |
| SCHEMBL3634459 | 0.78 | RAB9A (0.67) | TAS1R3TAS1R1TAS1R2NAMPTRAB9A | |
| SCHEMBL27102971 | 0.76 | TAS1R3 (0.78) | TAS1R3TAS1R1TAS1R2NAMPTRAB9A | |
| SCHEMBL5923924 | 0.76 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2NAMPTRAB9A | |
| SCHEMBL15029231 | 0.76 | TRAP1 (0.49) | TAS1R3TAS1R1TAS1R2NAMPTPOLB | |
| SCHEMBL21476810 | 0.75 | SMN1; SMN2 (0.55) | TAS1R3TAS1R1TAS1R2NAMPTRAB9A | |
| SCHEMBL5923951 | 0.73 | TAS1R3 (0.61) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |