Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046199 | 0.80 | HTT (0.38) | HTTOPRM1OPRD1ALDH1A1MAPT | |
| SCHEMBL8539087 | 0.72 | GRIN1 (0.40) | DHODHDRD2DRD4DRD3GRIN2B | |
| SCHEMBL20309767 | 0.72 | HTT (0.59) | HTTDHODHGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27922695 | 0.69 | SIRT1 (0.42) | OPRM1OPRD1GAAMEN1ALDH1A1 | |
| SCHEMBL6697342 | 0.69 | DRD2 (0.50) | DHODHALKBH3GAAMEN1ALDH1A1 | |
| SCHEMBL29067648 | 0.69 | TYMP (0.38) | OPRM1OPRD1GAAMEN1ALDH1A1 | |
| SCHEMBL20535512 | 0.67 | RHEB (0.67) | HTTDHODHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10814670 | 0.66 | L3MBTL1 (0.46) | OPRM1OPRD1MEN1ALDH1A1MAPT | |
| SCHEMBL13754917 | 0.66 | GAA (0.50) | HTTGAAMEN1ALDH1A1MAPT | |
| SCHEMBL9043260 | 0.66 | ALDH1A1 (0.47) | HTTDHODHALDH1A1MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100392-A2 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2007-09-07 | — | — | WO | disclosed |