Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484784 | 0.87 | SMN1; SMN2 (0.37) | TDP1KDM4EAPOBEC3GNPSR1GNRHR | |
| SCHEMBL3986121 | 0.75 | SMN1; SMN2 (0.39) | TDP1KDM4EAPOBEC3GNPSR1GNRHR | |
| SCHEMBL3913556 | 0.70 | ALDH1A1 (0.40) | TDP1NPSR1GNRHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3985349 | 0.68 | ALDH1A1 (0.34) | TDP1NPSR1GNRHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4488011 | 0.68 | SHMT2 (0.38) | SMN1; SMN2ALDH1A1L3MBTL1LMNATHRB | |
| SCHEMBL4493753 | 0.68 | CASR (0.38) | TDP1NPSR1GNRHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3986025 | 0.66 | HCRTR1 (0.37) | NPSR1GNRHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4483063 | 0.65 | SYK (0.36) | TDP1KDM4ENPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3991579 | 0.65 | SMN1; SMN2 (0.39) | TDP1KDM4EAPOBEC3GNPSR1GNRHR | |
| SCHEMBL4418581 | 0.64 | ADORA2B (0.32) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848711-A1 | FUNGICIDAL PYRAZINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006089060-A1 | FUNGICIDAL PYRAZINE DERIVATIVES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-08-24 | — | — | WO | disclosed |