Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.57 |
| ▸ | FLT4 | P35916 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 9/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | JAK1 | P23458 | 3/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316768 | 0.85 | FLT1 (0.54) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5319120 | 0.85 | VCP (0.62) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5318330 | 0.84 | IMPDH2 (0.48) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL14466043 | 0.84 | IMPDH2 (0.53) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL14465953 | 0.82 | FLT1 (0.58) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5318423 | 0.82 | VCP (0.56) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5321701 | 0.82 | ALOX5 (0.52) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5316815 | 0.82 | KDR (0.57) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5336408 | 0.80 | TUBB4A (0.42) | FLT1KDRIMPDH2VCPJAK1 | |
| SCHEMBL5338884 | 0.79 | FLT1 (0.59) | FLT1FLT4KDRIMPDH2VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |