Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95409 | 0.84 | TNKS (0.45) | HPGDPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL27770507 | 0.73 | PRSS1 (0.63) | SMN1; SMN2PRSS1ACRTDP1MEN1 | |
| SCHEMBL2974690 | 0.71 | MEN1 (0.66) | HPGDPOLBHTTTDP1MEN1 | |
| SCHEMBL6002933 | 0.70 | LMNA (0.38) | POLBSMN1; SMN2TDP1PAX8TLR9 | |
| SCHEMBL96528 | 0.70 | LPAR1 (0.54) | HPGDSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL31606631 | 0.69 | TSHR (0.40) | HPGDPOLBSMN1; SMN2KDM4EHTT | |
| SCHEMBL19577308 | 0.69 | GPBAR1 (0.52) | HPGDPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4526462 | 0.69 | HPGD (0.50) | HPGDSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL28773371 | 0.68 | PTGIR (0.48) | HPGDPOLBSMN1; SMN2KDM4EHTT | |
| SCHEMBL31606635 | 0.68 | CTSD (0.43) | SMN1; SMN2HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |