Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414871 | 0.85 | ALDH1A1 (0.55) | ITGAVSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL7200209 | 0.83 | PKM (0.51) | ITGAVSLC1A3SLC1A2SLC1A1KAT6A | |
| SCHEMBL8415212 | 0.82 | PKM (0.48) | ITGAVSLC1A3SLC1A2SLC1A1KAT6A | |
| SCHEMBL5899510 | 0.81 | ALDH1A1 (0.47) | ITGAVKAT6APKMMAPTSMN1; SMN2 | |
| SCHEMBL5899441 | 0.81 | KAT6A (0.57) | KAT6AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2842146 | 0.79 | MEP1B (0.68) | PKMMEP1B | |
| SCHEMBL15548708 | 0.79 | ALDH1A1 (0.53) | ITGAVSLC1A3SLC1A2SLC1A1KAT6A | |
| SCHEMBL5899544 | 0.78 | KAT6A (0.58) | KAT6AKMT2AMEN1CYP3A4HPGD | |
| SCHEMBL5320466 | 0.78 | ALDH1A1 (0.60) | KAT6ARAB9AKMT2AMEN1CYP3A4 | |
| SCHEMBL754844 | 0.78 | KMT2A (0.56) | KAT6ARAB9AKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114532-A1 | NOVEL CHALCONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT, METHOD FOR PREPARATION AND USES THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2007-10-11 | — | — | WO | disclosed |
| US-4372956-A | CARDIOTONIC AGENTS, VASODILATION | SANDOZ LTD. (CH) | 1983-02-08 | — | — | US | disclosed |
| EP-0029559-A2 | 5,10-dihydroimidazo(2,1-b)quinazolines, their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1981-06-03 | — | — | EP | disclosed |