Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 13/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899485 | 0.83 | KAT6A (0.63) | KAT6AGBA1 | |
| SCHEMBL22779445 | 0.82 | KAT6A (0.52) | KAT6AMEN1ALDH1A1KMT2AATM | |
| SCHEMBL5320463 | 0.81 | ITGAV (0.51) | KAT6AMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL6851861 | 0.81 | GBA1 (0.57) | KAT6AMEN1ALDH1A1KMT2AATM | |
| SCHEMBL15621004 | 0.79 | GBA1 (0.55) | KAT6AMEN1ALDH1A1KMT2AATM | |
| SCHEMBL5899544 | 0.78 | KAT6A (0.58) | KAT6AMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL23014361 | 0.78 | KAT6A (0.58) | KAT6AMEN1ALDH1A1KMT2A | |
| SCHEMBL2941286 | 0.76 | FABP4 (0.57) | KAT6AALDH1A1ATMGBA1 | |
| SCHEMBL5899510 | 0.76 | ALDH1A1 (0.47) | KAT6AALDH1A1MAPT | |
| SCHEMBL754844 | 0.74 | KMT2A (0.56) | KAT6AMEN1ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | KAT6A 2440/4885MEN1 1269/4885ALDH1A1 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.