Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243146 | 0.87 | CCR3 (0.49) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4239655 | 0.86 | F2 (0.50) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4247871 | 0.85 | KMT2A (0.62) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4250198 | 0.83 | SLC2A1 (0.53) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4243510 | 0.83 | FAAH (0.56) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4239616 | 0.82 | FAAH (0.61) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4252205 | 0.81 | HTR2A (0.43) | KMT2AGRIN2B | |
| SCHEMBL4252214 | 0.81 | KMT2A (0.47) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4244566 | 0.81 | ESRRG (0.49) | KMT2ACHRM2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5320493 | 0.80 | GAA (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |