SCHEMBL4243510

SCHEMBL4243510

Cc1ccc(CC2CCN(C(=O)NC(=O)c3ccc(O)cc3)CC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.56
TMEM97 Q5BJF2 1/20 0.49
KMT2A Q03164 3/20 0.49
MGLL Q99685 1/20 0.48
MEN1 O00255 2/20 0.47
POLB P06746 1/20 0.47
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4242910 0.88 KMT2A (0.47) FAAHKMT2AMEN1POLBGRIN2B
SCHEMBL4252214 0.88 KMT2A (0.47) FAAHKMT2AMEN1POLBGRIN2D
SCHEMBL4244566 0.88 ESRRG (0.49) FAAHKMT2AMEN1POLBGRIN2D
SCHEMBL4243146 0.88 CCR3 (0.49) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL4247871 0.88 KMT2A (0.62) FAAHKMT2AMGLLMEN1POLB
SCHEMBL4239616 0.88 FAAH (0.61) FAAHKMT2AMEN1POLBGRIN2D
SCHEMBL4241032 0.87 SMN1; SMN2 (0.59) KMT2AMGLLMEN1POLBGRIN1
SCHEMBL4250198 0.86 SLC2A1 (0.53) FAAHKMT2AMGLLMEN1GRIN2D
SCHEMBL4245175 0.84 FAAH (0.58) FAAHTMEM97KMT2AMEN1POLB
SCHEMBL5320489 0.83 KMT2A (0.46) FAAHKMT2AMEN1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090170901-A1 Benzoyl Urea Derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2009-07-02 US claimed
EP-1771429-A1 NEW BENZOYL UREA DERIVATIVES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2007-04-11 EP claimed
WO-2006010966-A1 NEW BENZOYL UREA DERIVATIVES Richter Gedeon Vegyészeti Gyár Rt. (HU) 2006-02-02 WO claimed
US-20090170901-A1 Benzoyl Urea Derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2009-07-02 US disclosed
EP-1771429-A1 NEW BENZOYL UREA DERIVATIVES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2007-04-11 EP disclosed
WO-2006010966-A1 NEW BENZOYL UREA DERIVATIVES Richter Gedeon Vegyészeti Gyár Rt. (HU) 2006-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170901-A1 Benzoyl Urea Derivatives OPRM1, GRIN2C, GRIN3A FAAH 1415/4885TMEM97 180/4885KMT2A 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.