Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250198 | 0.88 | SLC2A1 (0.53) | CCR3GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4247871 | 0.88 | KMT2A (0.62) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4243510 | 0.88 | FAAH (0.56) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4239616 | 0.88 | FAAH (0.61) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5320489 | 0.87 | KMT2A (0.46) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4239655 | 0.86 | F2 (0.50) | CCR3GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4252214 | 0.86 | KMT2A (0.47) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4244566 | 0.86 | ESRRG (0.49) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4245364 | 0.85 | CCR3 (0.53) | CCR3GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4241032 | 0.85 | SMN1; SMN2 (0.59) | CCR3GRIN2BGRIN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | claimed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | claimed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | CCR3 1472/4885GRIN2B 7/4885GRIN2D 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.