Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 5/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 5/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.45 |
| ▸ | CACNG3 | O60359 | 5/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.45 |
| ▸ | CACNB3 | P54284 | 5/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.45 |
| ▸ | CACNG7 | P62955 | 5/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.45 |
| ▸ | CACNG1 | Q06432 | 5/20 | 0.45 |
| ▸ | CACNB2 | Q08289 | 5/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.45 |
| ▸ | CACNA1E | Q15878 | 5/20 | 0.45 |
| ▸ | CACNA2D4 | Q7Z3S7 | 5/20 | 0.45 |
| ▸ | CACNA2D3 | Q8IZS8 | 5/20 | 0.45 |
| ▸ | CACNG8 | Q8WXS5 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317466 | 0.90 | HDAC1 (0.45) | HDAC1HDAC8HDAC6ICMTSLC5A2 | |
| SCHEMBL5342941 | 0.90 | PLA2G2A (0.51) | HDAC1HDAC8HDAC6ICMTPTPN1 | |
| SCHEMBL5337560 | 0.89 | HDAC6 (0.55) | HDAC1HDAC8HDAC6PTPN1PTPN2 | |
| SCHEMBL5320802 | 0.89 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ICMTPTPN1 | |
| SCHEMBL5324927 | 0.89 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ICMTPTPN1 | |
| SCHEMBL5339333 | 0.88 | PLA2G2A (0.54) | HDAC1HDAC8HDAC6ICMTPTPN1 | |
| SCHEMBL14467245 | 0.86 | CACNB4 (0.45) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL5318293 | 0.79 | IDO1 (0.45) | HDAC1HDAC8HDAC6PTPN1PTPN2 | |
| SCHEMBL5348172 | 0.78 | HDAC6 (0.48) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5389043 | 0.78 | IDO1 (0.42) | HDAC1HDAC8HDAC6PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081755-A2 | INDOLE-BENZIMIDAZOLE AND INDAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | METABASIS THERAPEUTICS, INC. (US) | 2007-07-19 | — | — | WO | claimed |