Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324314 | 0.77 | NQO2 (0.57) | BCHENQO2SCN1ASCN2ASCN3A | |
| SCHEMBL5321679 | 0.70 | CA2 (0.58) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3910923 | 0.68 | HSD17B10 (0.41) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3937795 | 0.67 | ALDH1A1 (0.60) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18077873 | 0.67 | FABP4 (0.46) | SCN1ASCN2ASCN3AKDM4EALDH1A1 | |
| SCHEMBL20577411 | 0.64 | ALDH1A1 (0.44) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4304817 | 0.64 | L3MBTL1 (0.57) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28028848 | 0.62 | CA1 (0.57) | KDM4EALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL3763664 | 0.62 | KDM4E (0.67) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28124395 | 0.62 | HSD17B10 (0.36) | SLC2A1KDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007108743-A2 | NOVEL QUINAZOLINES AS 5-HT6 MODULATORS II | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | WO | claimed |