SCHEMBL5320927

SCHEMBL5320927

C=CCSOCC(O)CO

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27632773 0.79 LMNA (0.32) ALDH1A1LMNA
Glycerin SCHEMBL9376563 0.78 ALDH1A1 (0.41) ALDH1A1LMNACA1CA2CA7
SCHEMBL27697564 0.75
SCHEMBL27816434 0.71
SCHEMBL9376342 0.71 ALDH1A1 (0.32) ALDH1A1LMNA
SCHEMBL11881950 0.71 CA1 (0.36) ALDH1A1LMNACA1CA2CA7
Diallyl Sulfide SCHEMBL9376569 0.70 ALOX5 (0.58) ALDH1A1LMNA
SCHEMBL75408 0.69 LMNA (0.44) ALDH1A1LMNA
SCHEMBL1270184 0.69 LMNA (0.44) ALDH1A1LMNA
SCHEMBL11661082 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011011710-A1 METHODS OF TREATING VIRAL INFECTIONS CHIMERIX, INC. (US) 2011-01-27 WO claimed
EP-0380409-B1 Process for the preparation of non-ionic surface-active agents from isopropylidene-1,2 epoxypropyl-3 glycerol and from hydroxylated compounds, non-ionic surface-active agents and use of same OREAL (FR) 1994-06-01 EP claimed
US-4105580-A POLYGLYCEROL NON-IONIC SURFACE ACTIVE AGENTS AND PROCESS FOR PREPARING THE SAME FROM CRUDE GLYCIDOL L'OREAL (FR) 1978-08-08 US claimed
EP-2841162-A1 A METHOD OF MITIGATING VIRUS ASSOCIATED END-ORGAN DAMAGE Chimerix, Inc. (US) 2015-03-04 EP disclosed
EP-2770834-A1 HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION Chimerix, Inc. (US) 2014-09-03 EP disclosed
WO-2013163509-A1 A METHOD OF MITIGATING VIRUS ASSOCIATED END-ORGAN DAMAGE CHIMERIX, INC. (US) 2013-10-31 WO disclosed
WO-2013063436-A1 HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION CHIMERIX, INC. (US) 2013-05-02 WO disclosed
EP-1868628-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS Chimerix, Inc. (US) 2007-12-26 EP disclosed
WO-2006110655-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS CHIMERIX, INC. (US) 2006-10-19 WO disclosed