Glycerin

Glycerin

SCHEMBL9376563

C=CCSOSCC=C.OCC(O)CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
TRPA1 O75762 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX5 P09917 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2520683 0.80 TRPA1 (0.38) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL241846 0.80
SCHEMBL5320927 0.78 ALDH1A1 (0.32) ALDH1A1LMNACA1CA2CA7
Diallyl Sulfide SCHEMBL9376569 0.78 ALOX5 (0.58) ALDH1A1LMNATRPA1CYP3A4HPGD
Hydrochloric Acid SCHEMBL5912673 0.77 TRPA1 (0.44) ALDH1A1TRPA1CYP3A4HPGDALOX15
Glycerin SCHEMBL569689 0.72 LMNA (0.60) ALDH1A1LMNACA1CA2CA7
Allylamine SCHEMBL899541 0.70 ALDH1A1 (0.50) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL5320940 0.70
Glycerin SCHEMBL27945356 0.69 LMNA (0.56) ALDH1A1LMNACA1CA2CA7
Glycerin SCHEMBL9617071 0.69 CA1 (0.52) ALDH1A1LMNACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0380409-B1 Process for the preparation of non-ionic surface-active agents from isopropylidene-1,2 epoxypropyl-3 glycerol and from hydroxylated compounds, non-ionic surface-active agents and use of same OREAL (FR) 1994-06-01 EP claimed
US-4105580-A POLYGLYCEROL NON-IONIC SURFACE ACTIVE AGENTS AND PROCESS FOR PREPARING THE SAME FROM CRUDE GLYCIDOL L'OREAL (FR) 1978-08-08 US claimed