Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477269 | 0.89 | ALDH1A1 (0.39) | CTSBSLC6A3RIPK1CASP3SENP8 | |
| SCHEMBL3686370 | 0.80 | MAPK1 (0.36) | SLC6A3GAANPC1POLBRAB9A | |
| SCHEMBL156999 | 0.76 | MAPK1 (0.34) | SLC6A3GAANPC1POLBRAB9A | |
| SCHEMBL4707996 | 0.70 | SLC6A3 (0.52) | SLC6A3ALDH1A1 | |
| SCHEMBL21765808 | 0.68 | CES2 (0.41) | SLC6A3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1477896 | 0.67 | MAPT (0.39) | GAANPC1POLBRAB9AALDH1A1 | |
| SCHEMBL3091676 | 0.65 | SMN1; SMN2 (0.39) | SLC6A3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL3826078 | 0.65 | SMN1; SMN2 (0.39) | SLC6A3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL4727041 | 0.65 | PSEN1 (0.39) | SLC6A3GAANPC1POLBRAB9A | |
| Malonic Acid Diethyl Ester SCHEMBL8019960 | 0.65 | GAA (0.47) | GAAPOLBRAB9AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118844-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING HARMFUL FUNGI AND COMPOSITIONS COMPRISING THEM | BASF SE (DE) | 2007-10-25 | — | — | WO | disclosed |