SCHEMBL532185

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL532008	0.88	ERN1 (0.36)	L3MBTL1ERN1KDM4EPOLBCTDSP1
	SCHEMBL533040	0.77	ALDH1A1 (0.42)	ERN1KDM4EPOLBKMT2AALDH1A1
	SCHEMBL5350350	0.73	ALDH5A1 (0.48)	POLBKMT2AMEN1ALDH1A1MAPT
	SCHEMBL531886	0.73	ALDH5A1 (0.48)	POLBKMT2AMEN1ALDH1A1MAPT
	SCHEMBL30806257	0.73	L3MBTL1 (0.48)	L3MBTL1KMT2AMEN1ALDH1A1MAPT
	SCHEMBL9824194	0.73	KMT2A (0.56)	L3MBTL1TDP1KMT2AMEN1ALDH1A1
	SCHEMBL532720	0.72	ALDH1A1 (0.43)	ERN1KDM4EALDH1A1MAPTCYP3A4
	SCHEMBL532738	0.72	ALDH1A1 (0.42)	L3MBTL1ERN1KDM4EKMT2AMEN1
	SCHEMBL15058014	0.71	KMT2A (0.46)	ERN1KMT2AALDH1A1F9PLAU
	SCHEMBL531788	0.71	ALDH1A1 (0.49)	POLBTDP1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.