SCHEMBL533040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL532720	0.86	ALDH1A1 (0.43)	ALDH1A1KDM4ECYP3A4MAPTALOX15
	SCHEMBL532738	0.85	ALDH1A1 (0.42)	ALDH1A1KDM4ECYP3A4MAPTALOX15
	SCHEMBL30806648	0.80	ALDH1A1 (0.39)	ALDH1A1CYP3A4MAPTPDK1KMT2A
	SCHEMBL5210790	0.79	ALDH1A1 (0.61)	ALDH1A1KDM4ECYP3A4MAPTALOX15
	SCHEMBL5350350	0.78	ALDH5A1 (0.48)	ALDH1A1MAPTPDK1KMT2APOLB
	SCHEMBL531788	0.78	ALDH1A1 (0.49)	ALDH1A1MAPTKMT2APOLB
	SCHEMBL531886	0.78	ALDH5A1 (0.48)	ALDH1A1MAPTPDK1KMT2APOLB
	SCHEMBL9203475	0.77	RAB9A (0.51)	ALDH1A1MAPTKMT2A
	SCHEMBL9203477	0.77	RAB9A (0.51)	ALDH1A1MAPTKMT2A
	SCHEMBL30806257	0.77	L3MBTL1 (0.48)	ALDH1A1MAPTPDK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.