Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153089 | 0.82 | CYP2A13 (0.60) | DRD1DRD4DRD5KDM4ETSHR | |
| SCHEMBL23926333 | 0.80 | SIGMAR1 (0.61) | MEN1KMT2AKDM4ETSHRHRH3 | |
| SCHEMBL10454920 | 0.80 | HRH3 (0.72) | MEN1KMT2AKDM4ETSHRHRH3 | |
| SCHEMBL6152429 | 0.79 | ALDH1A1 (0.53) | KMT2ADRD1DRD4DRD5KDM4E | |
| SCHEMBL21886975 | 0.78 | LTA4H (0.65) | MEN1KMT2ADRD1DRD4DRD5 | |
| SCHEMBL5321100 | 0.77 | ATM (0.58) | KMT2AATMKDM4ETSHRHRH3 | |
| SCHEMBL1854821 | 0.77 | HTR1A (0.56) | KDM4EHRH3 | |
| SCHEMBL27466067 | 0.76 | ABCB1 (0.52) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL4327006 | 0.76 | MPO (0.75) | MEN1KMT2AKDM4ETSHRTDP1 | |
| SCHEMBL6153236 | 0.76 | ALDH1A1 (0.52) | DRD1DRD4DRD5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114672-A1 | AGENT FOR THE PREVENTION AND TREATMENT OF METABOLIC BONE DISEASE BY ENHANCING OSTEOPROTEGERIN SECRETION | OSCOTEC INC. (KR) | 2007-10-11 | — | — | WO | disclosed |