Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412331 | 0.86 | SMN1; SMN2 (0.36) | TDP1HRH3ADRB2ADRB1ADRB3 | |
| SCHEMBL10309668 | 0.79 | HRH3 (0.50) | ROCK2ROCK1LMNATDP1HRH3 | |
| SCHEMBL14225111 | 0.76 | ROCK2 (0.40) | ROCK2ROCK1LMNATDP1SMN1; SMN2 | |
| SCHEMBL254889 | 0.76 | TP53 (0.44) | ROCK2ROCK1LMNATDP1SMN1; SMN2 | |
| SCHEMBL1467609 | 0.76 | TP53 (0.44) | ROCK2ROCK1LMNATDP1SMN1; SMN2 | |
| SCHEMBL9237133 | 0.76 | TP53 (0.44) | ROCK2ROCK1LMNATDP1SMN1; SMN2 | |
| SCHEMBL27268590 | 0.76 | GABRP (0.43) | HRH3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5326410 | 0.75 | THRA (0.35) | ROCK2ROCK1HCRTR2 | |
| SCHEMBL19480999 | 0.75 | ROCK2 (0.39) | ROCK2ROCK1LMNATDP1 | |
| SCHEMBL27579802 | 0.74 | SMN1; SMN2 (0.40) | HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135533-A1 | PROCESS FOR PREPARING NATEGLINIDE B-TYPE CRYSTALS | AUROBINDO PHARMA LIMITED (IN) | 2007-11-29 | — | — | WO | disclosed |