Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326409 | 0.95 | THRA (0.38) | THRATHRBHCRTR2ROCK2ROCK1 | |
| SCHEMBL5322016 | 0.75 | ROCK2 (0.36) | HCRTR2ROCK2ROCK1 | |
| SCHEMBL26355344 | 0.71 | THRA (0.39) | THRATHRB | |
| SCHEMBL9939580 | 0.70 | THRA (0.40) | THRATHRB | |
| SCHEMBL25010777 | 0.70 | THRA (0.32) | THRATHRB | |
| SCHEMBL13246740 | 0.69 | MAPT (0.40) | HCRTR2 | |
| SCHEMBL21363305 | 0.66 | MMP8 (0.38) | — | |
| SCHEMBL20979085 | 0.66 | SLC1A3 (0.33) | — | |
| SCHEMBL13267646 | 0.66 | MAPT (0.43) | ROCK2ROCK1 | |
| SCHEMBL24370551 | 0.66 | PLA2G10 (0.38) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135533-A1 | PROCESS FOR PREPARING NATEGLINIDE B-TYPE CRYSTALS | AUROBINDO PHARMA LIMITED (IN) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135533-A1 | PROCESS FOR PREPARING NATEGLINIDE B-TYPE CRYSTALS | AUROBINDO PHARMA LIMITED (IN) | 2007-11-29 | — | — | WO | disclosed |