Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 11/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PRKCI | P41743 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729323 | 0.88 | ALDH1A1 (0.79) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL689790 | 0.88 | ALDH1A1 (0.78) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL15940127 | 0.85 | ALDH1A1 (0.74) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3975901 | 0.85 | ALDH1A1 (0.73) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3995640 | 0.83 | ALDH1A1 (0.76) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL688523 | 0.83 | PRKCZ (1.00) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3979210 | 0.82 | MAPT (0.69) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL13837659 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL13837695 | 0.76 | PRKCZ (1.00) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL8288639 | 0.75 | ALDH1A1 (0.76) | ALDH1A1MAPTHSD17B10LMNAPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007102679-A1 | NOVEL THIENOPYRIMIDINE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | JE IL PHARMACEUTICAL CO., LTD. (KR) | 2007-09-13 | — | — | WO | disclosed |