Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975901 | 0.89 | ALDH1A1 (0.73) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3975220 | 0.85 | PRKCZ (0.58) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3975200 | 0.85 | PRKCZ (0.48) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL27729323 | 0.83 | ALDH1A1 (0.79) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3975696 | 0.82 | PRKCZ (0.45) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3980156 | 0.82 | PRKCZ (0.45) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL5322173 | 0.82 | ALDH1A1 (1.00) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3972011 | 0.81 | PRKCZ (0.57) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3974360 | 0.79 | PRKCZ (0.62) | MAPTALDH1A1HSD17B10LMNAPRKCZ | |
| SCHEMBL3972275 | 0.79 | RORB (0.49) | MAPTALDH1A1HSD17B10LMNAPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |