Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PRKCI | P41743 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975901 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL5322173 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL689790 | 0.84 | ALDH1A1 (0.78) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL2368746 | 0.83 | PRKCZ (0.58) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3979210 | 0.83 | MAPT (0.69) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL1799330 | 0.79 | KMT2A (0.69) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL12465745 | 0.79 | HSD17B10 (0.51) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL4932598 | 0.79 | HSD17B10 (0.51) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL12466203 | 0.79 | HSD17B10 (0.51) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL15940127 | 0.78 | ALDH1A1 (0.74) | ALDH1A1MAPTHSD17B10LMNAPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351453-A | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-21 | — | — | CN | disclosed |