Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165811 | 0.90 | PTGS1 (0.60) | PTGS1PTGS2 | |
| SCHEMBL6166234 | 0.90 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL6165447 | 0.89 | — | — | |
| SCHEMBL6166207 | 0.89 | PTGS2 (0.59) | PTGS1PTGS2 | |
| SCHEMBL6169041 | 0.88 | — | — | |
| SCHEMBL6960562 | 0.86 | — | — | |
| SCHEMBL6164793 | 0.85 | — | — | |
| SCHEMBL6166360 | 0.85 | — | — | |
| SCHEMBL6169378 | 0.84 | — | — | |
| SCHEMBL6164498 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233959-B1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PROD INC (US) | 2005-03-16 | — | — | EP | claimed |
| US-20040266832-A1 | Crystal forms of 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl pyridine | PFIZER PRODUCTS, INC. | 2004-12-30 | — | — | US | claimed |
| US-20030236258-A1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2003-12-25 | — | — | US | claimed |
| CN-1423646-A | Hetero cyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-06-11 | — | — | CN | claimed |
| US-6531492-B1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2003-03-11 | — | — | US | claimed |
| EP-1233959-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | Pfizer Products Inc. (US) | 2002-08-28 | — | — | EP | claimed |
| WO-2001040216-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | claimed |
| US-20230034183-A1 | AQUEOUS SUNCARE FORMULATION | DOW GLOBAL TECHNOLOGIES LLC | 2023-02-02 | — | — | US | disclosed |
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |
| US-20050175570-A1 | Composition containing a semi-crystalline polymer and a polyvinylpyrrolidone/alpha-olefin copolymer | L'OREAL (FR) | 2005-08-11 | — | — | US | disclosed |
| EP-1233959-B1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PROD INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6846930-B2 | Heterocyclo-alkylsulfonyl pyrazole derivatives | PFIZER INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040266832-A1 | Crystal forms of 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl pyridine | PFIZER PRODUCTS, INC. | 2004-12-30 | — | — | US | disclosed |
| US-6646128-B2 | Antiinflammatory agents | PFIZER INC. | 2003-11-11 | — | — | US | disclosed |
| CN-1423646-A | Hetero cyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-06-11 | — | — | CN | disclosed |
| US-20030100765-A1 | Process for preparing heterocyclo-alkysulfonyl pyrazole derivatives | PFIZER INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003029244-A1 | PROCESS FOR PREPARING PYRIDYL-ALKYLSULFONYL PYRAZOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2003-04-10 | — | — | WO | disclosed |
| US-6531492-B1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PFIZER INC. | 2003-03-11 | — | — | US | disclosed |
| EP-1233959-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | Pfizer Products Inc. (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001040216-A1 | HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236258-A1 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents | PTGS1, SULT2A1, PTGES3 | PTGS1 1/4885PTGS2 4/4885 |
| US-20040266832-A1 | Crystal forms of 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl pyridine | TPMT, PKD1, PDXK | PTGS1 3402/4885PTGS2 3908/4885 |
| US-20030100765-A1 | Process for preparing heterocyclo-alkysulfonyl pyrazole derivatives | IL1R1, IRAK1, IRAK4 | PTGS1 54/4885PTGS2 217/4885 |
| US-20050175570-A1 | Composition containing a semi-crystalline polymer and a polyvinylpyrrolidone/alpha-olefin copolymer | POLL, CUTA, COL1A1 | PTGS1 1219/4885PTGS2 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.