Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703831 | 0.86 | ALDH1A1 (0.47) | LMNAKMT2AMEN1ALDH1A1APOBEC3A | |
| SCHEMBL4553054 | 0.84 | LMNA (0.47) | LMNAALDH1A1CES2CES1GAA | |
| SCHEMBL17956727 | 0.79 | ALDH1A1 (0.55) | LMNAALDH1A1CES2CES1MAPT | |
| SCHEMBL34694 | 0.77 | LMNA (1.00) | LMNAKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL27466007 | 0.77 | LMNA (0.47) | LMNAKMT2AMEN1ALDH1A1CES2 | |
| SCHEMBL27438055 | 0.77 | CES2 (0.47) | LMNAALDH1A1CES2CES1 | |
| SCHEMBL5322597 | 0.76 | LMNA (0.51) | LMNAKMT2AMEN1ALDH1A1CES2 | |
| SCHEMBL44517 | 0.75 | LMNA (0.57) | LMNAALDH1A1CES2CES1MAPT | |
| SCHEMBL27796137 | 0.75 | RORC (0.58) | LMNAKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1669579 | 0.74 | LMNA (0.74) | LMNAKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858868-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006094840-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-09-14 | — | — | WO | disclosed |