Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17956727 | 0.84 | ALDH1A1 (0.55) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27489899 | 0.81 | CES2 (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27438055 | 0.81 | CES2 (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL44517 | 0.80 | LMNA (0.57) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27703831 | 0.80 | ALDH1A1 (0.47) | LMNACES2CES1ALDH1A1MEN1 | |
| SCHEMBL21404273 | 0.79 | LMNA (0.45) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL19952905 | 0.78 | CES2 (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL3521745 | 0.78 | LMNA (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL5322601 | 0.77 | LMNA (0.61) | LMNACES2CES1ALDH1A1MEN1 | |
| SCHEMBL27796137 | 0.77 | RORC (0.58) | LMNAMAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149287-A | Process for the preparation of unsaturated amino compounds | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | CN | disclosed |