SCHEMBL5322844

SCHEMBL5322844

C1=CC2=CC=C1C2.CCCC[Si](ON)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7408504 0.86 LTA4H (0.36) PTGS2LTA4H
SCHEMBL875722 0.72 LTA4H (0.38) PTGS2LTA4H
SCHEMBL7529688 0.71 LTA4H (0.37) PTGS2LTA4H
SCHEMBL2655578 0.71 LTA4H (0.37) PTGS2LTA4H
SCHEMBL1950697 0.70 AOC3 (0.30)
SCHEMBL2655575 0.70 LTA4H (0.36) PTGS2LTA4H
SCHEMBL3481751 0.70 LTA4H (0.36) PTGS2LTA4H
SCHEMBL11265902 0.69 SOAT1 (0.42) LTA4H
SCHEMBL3481385 0.68 LTA4H (0.39) PTGS2LTA4H
SCHEMBL9504610 0.68 LTA4H (0.33) PTGS2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007102888-A2 METHODS OF TREATING CANCER WITH DOXAZOLIDINE AND PRODRUGS THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2007-09-13 WO disclosed