Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755726 | 0.89 | HPGD (1.00) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL835108 | 0.89 | HPGD (1.00) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28193245 | 0.87 | MAPT (0.69) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL17187946 | 0.87 | MAPT (0.69) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL75640 | 0.87 | MAPT (0.69) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27858043 | 0.84 | MAPT (0.67) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL17180520 | 0.84 | MAPT (0.67) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9475945 | 0.83 | SRD5A2 (0.61) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8967091 | 0.83 | SRD5A2 (0.61) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| Nitrogen SCHEMBL27858242 | 0.82 | MAPT (0.64) | HPGDLMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-08-30 | — | — | US | disclosed |
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | U.S. DEPARTMENT OF ENERGY | 2018-12-27 | — | — | US | disclosed |
| EP-1349841-B1 | ANILINOPYRIMIDINE DERIVATIVES AS IKK INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO | SIGNAL PHARM LLC (US) | 2009-12-02 | — | — | EP | disclosed |
| US-7442699-B2 | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442699-B2 | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-10-28 | — | — | US | disclosed |
| US-7429599-B2 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429599-B2 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |
| US-20070082934-A1 | Substituted 4-aryloxy and 4-arylsulfanyl-phenyl-2-aminothiazoles as inhibitors of cell proliferation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2007-04-12 | — | — | US | disclosed |
| WO-2005044263-A1 | SUBSTITUTED 4-ARYLOXY AND 4-ARYLSULFANYL-PHENYL-2-AMINOTHIAZOLES AS INHIBITORS OF CELL PROLIFERATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2004084901-A1 | METHODS FOR TREATING OR PREVENTING AN INFLAMMATORY OR METABOLIC CONDITION BY INHIBITING JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2004-10-07 | — | — | WO | disclosed |
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | TST, CBS, CRY2 | HPGD 1394/4885LMNA 4215/4885L3MBTL1 1004/4885 |
| US-20070082934-A1 | Substituted 4-aryloxy and 4-arylsulfanyl-phenyl-2-aminothiazoles as inhibitors of cell proliferation | MKI67, CCNI, CDK4 | HPGD 2433/4885LMNA 4630/4885L3MBTL1 2111/4885 |
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | TST, CBS, CRY2 | HPGD 1394/4885LMNA 4215/4885L3MBTL1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.