Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALOX15B | O15296 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186907 | 0.82 | CYP3A4 (0.44) | FDPSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL26964192 | 0.82 | ALDH1A1 (0.42) | FDPSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28459041 | 0.81 | HTR6 (0.43) | FDPSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9372056 | 0.79 | TSHR (0.46) | CYP1A2CYP3A4CYP2D6GAASMN1; SMN2 | |
| SCHEMBL1407881 | 0.71 | CYP3A4 (0.46) | FDPSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8465594 | 0.70 | SMN1; SMN2 (0.36) | FDPSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9796329 | 0.69 | CA1 (0.43) | GAAPTGS1PTGS2CA12CA1 | |
| SCHEMBL9372316 | 0.69 | LMNA (0.40) | L3MBTL1GAACA12CA1CA2 | |
| SCHEMBL27544735 | 0.69 | CYP2A6 (0.56) | CYP3A4L3MBTL1GAAPTGS2MAPK1 | |
| SCHEMBL6693696 | 0.69 | FTO (0.34) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089069-A1 | PHENYL IMIDAZOL SULFONAMIDE DERIVATIVES, THE PREPARATION METHOD THEREOF AND THE WHITENING COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-08-09 | — | — | WO | disclosed |
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | disclosed |
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | disclosed |