SCHEMBL7186907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12362850	0.83	ENPP2 (0.41)	CYP3A4PTGS2ALDH1A1NR1I2HSD11B1
	SCHEMBL5323928	0.82	FDPS (0.42)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL26964192	0.82	ALDH1A1 (0.42)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL28459041	0.81	HTR6 (0.43)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL8811494	0.74	PTGS2 (0.54)	PTGS2HSD11B1
	SCHEMBL12362841	0.72	ESR1 (0.42)	NR1I2HSD11B1
	SCHEMBL7290958	0.72	PDE3B (0.51)	CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1
	SCHEMBL19071797	0.71	KMT2A (0.42)	SMN1; SMN2RAB9APTGS2ALDH1A1MEN1
	SCHEMBL8811591	0.71	PTGS2 (0.56)	PTGS2
	SCHEMBL2336960	0.71	CYP3A4 (0.69)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.