Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.44 |
| ▸ | CES1 | P23141 | 7/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | LIPA | P38571 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542324 | 0.85 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9059827 | 0.83 | FAAH (0.68) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL19320231 | 0.81 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3489632 | 0.81 | FAAH (0.69) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6152180 | 0.81 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL810081 | 0.78 | — | — | |
| SCHEMBL811057 | 0.78 | LIPA (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL14304568 | 0.76 | — | — | |
| SCHEMBL30495532 | 0.76 | LIPA (0.35) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9190607 | 0.75 | CES1 (0.43) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121851-A1 | LIGHTENING AND/OR COLOURING AGENTS COMPRISING HALOGENATED KETONES | HENKEL AG & CO. KGAA (DE) | 2007-11-01 | — | — | WO | claimed |