Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.39 |
| ▸ | CES1 | P23141 | 8/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LIPA | P38571 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323967 | 0.81 | FAAH (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL5728393 | 0.76 | FAAH (0.34) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL132627 | 0.75 | FAAH (0.33) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL16207954 | 0.75 | FFAR3 (0.43) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL11542324 | 0.73 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL20680198 | 0.72 | THRB (0.35) | — | |
| SCHEMBL810081 | 0.71 | — | — | |
| SCHEMBL19320231 | 0.70 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL14304568 | 0.69 | — | — | |
| SCHEMBL9190607 | 0.68 | CES1 (0.43) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953041-B2 | Compositions of transition metal species in dense phase carbon dioxide and methods of use thereof | MICELL TECHNOLOGIES, INC. (US) | 2005-10-11 | — | — | US | disclosed |
| EP-1549784-A2 | COMPOSITIONS OF TRANSITION METAL SPECIES IN DENSE PHASE CARBON DIOXIDE AND METHODS OF USE THEREOF | Micell Technologies, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033758-A2 | COMPOSITIONS OF TRANSITION METAL SPECIES IN DENSE PHASE CARBON DIOXIDE AND METHODS OF USE THEREOF | MICELL TECHNOLOGIES, INC. (US) | 2004-04-22 | — | — | WO | disclosed |
| US-20040071873-A1 | Compositions of transition metal species in dense phase carbon dioxide and methods of use thereof | MICELL TECHNOLOGIES, INC. | 2004-04-15 | — | — | US | disclosed |