Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326276 | 0.86 | ROCK2 (0.44) | ROCK2ROCK1PSMB5ALDH1A1MMEL1 | |
| SCHEMBL5324896 | 0.81 | NR1H4 (0.55) | PSMB5ALDH1A1DNMT3AMEN1USP2 | |
| SCHEMBL5325179 | 0.81 | NR1H4 (0.55) | PSMB5ALDH1A1DNMT3AMEN1USP2 | |
| SCHEMBL5326665 | 0.81 | NR1H4 (0.55) | PSMB5ALDH1A1DNMT3AMEN1USP2 | |
| SCHEMBL5325174 | 0.80 | ALDH1A1 (0.70) | PSMB5ALDH1A1DNMT3ALMNAACACB | |
| SCHEMBL5327174 | 0.79 | ALDH1A1 (0.51) | PSMB5ALDH1A1DNMT3AMEN1KMT2A | |
| SCHEMBL14398212 | 0.76 | ALDH1A1 (0.48) | ALDH1A1DNMT3AMEN1KMT2AHSD17B10 | |
| SCHEMBL22419895 | 0.75 | TTR (0.50) | ALDH1A1KDM4EMEN1USP2DHFR | |
| SCHEMBL13243349 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1USP2DHFR | |
| SCHEMBL5325161 | 0.73 | ACACB (0.48) | PSMB5ALDH1A1DNMT3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | claimed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |