Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | NUDT15 | Q9NV35 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 7/20 | 0.48 |
| ▸ | F10 | P00742 | 7/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5296078 | 0.85 | HRH3 (0.52) | HRH3F10ATMTDP1L3MBTL1 | |
| SCHEMBL5323125 | 0.84 | HRH3 (0.51) | HRH3F10TDP1L3MBTL1MAPT | |
| SCHEMBL5326524 | 0.84 | L3MBTL1 (0.54) | NUDT15GHSRF10ATML3MBTL1 | |
| SCHEMBL5327115 | 0.83 | GHSR (0.50) | NUDT15GHSRF10ATMTDP1 | |
| SCHEMBL5324555 | 0.81 | ATM (0.63) | NUDT15GHSRF10ATMTDP1 | |
| SCHEMBL5090977 | 0.77 | F10 (0.68) | HRH3F10 | |
| SCHEMBL4882732 | 0.76 | LSS (0.47) | HRH3F10L3MBTL1 | |
| SCHEMBL5322343 | 0.72 | ALDH1A1 (0.53) | F10ATML3MBTL1MAPT | |
| SCHEMBL1639565 | 0.71 | HRH3 (1.00) | HRH3 | |
| SCHEMBL6152253 | 0.69 | F10 (0.65) | F10ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |