Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.50 |
| ▸ | NUDT15 | Q9NV35 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327658 | 0.84 | L3MBTL1 (0.42) | ATMF10MAPTTDP1L3MBTL1 | |
| SCHEMBL5326524 | 0.84 | L3MBTL1 (0.54) | GHSRNUDT15ATMF10MAPT | |
| SCHEMBL5324555 | 0.83 | ATM (0.63) | GHSRNUDT15ATMF10TDP1 | |
| SCHEMBL5324846 | 0.83 | HRH3 (0.54) | GHSRNUDT15ATMF10MAPT | |
| SCHEMBL5327112 | 0.80 | GHSR (0.49) | GHSR | |
| SCHEMBL5093870 | 0.75 | F10 (0.66) | F10 | |
| SCHEMBL6151827 | 0.74 | F10 (0.63) | ATMF10MAPTSMN1; SMN2 | |
| SCHEMBL5322343 | 0.72 | ALDH1A1 (0.53) | ATMF10MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6152077 | 0.72 | F10 (0.63) | ATMF10MAPTSMN1; SMN2 | |
| SCHEMBL5735457 | 0.70 | F10 (0.58) | ATMF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |