SCHEMBL532479

SCHEMBL532479

Nc1ncnc2c1c(C#CCNC(=O)C(F)(F)F)nn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATG7 O95352 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532480 1.00 ATG7 (0.49) ATG7
SCHEMBL12762313 1.00 ATG7 (0.49) ATG7
SCHEMBL21585106 0.84 CA2 (0.49) ATG7
SCHEMBL22327353 0.84 CA2 (0.49) ATG7
SCHEMBL12047324 0.84 CA2 (0.49) ATG7
SCHEMBL21912256 0.84 CA2 (0.49) ATG7
SCHEMBL13669400 0.83 ATG7 (0.50) ATG7
SCHEMBL13337884 0.82 LMNA (0.36) ATG7
SCHEMBL13251805 0.82 LMNA (0.36) ATG7
SCHEMBL887667 0.82 ATG7 (0.53) ATG7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235938-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2012-02-08 EP disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 US disclosed
US-7662942-B2 Oligonucleotide probes containing two labels useful in hybridization assays Elitech Holdings, B.V. (NL) 2010-02-16 US disclosed
US-20060292589-A1 Oligonucleotide probes containing two labels useful in hybridization assays EPOCH BIOSCIENCES, INC. (US) 2006-12-28 US disclosed
US-20040081959-A9 Using oligonucleotide detectors; hybridization analyzing EPOCH BIOSCIENCES, INC. (US) 2004-04-29 US disclosed
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression EPOCH BIOSCIENCES, INC. (US) 2003-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS DDX5, DDX21, DCLRE1B ATG7 4097/4885
US-20040081959-A9 Using oligonucleotide detectors; hybridization analyzing DCLRE1B, DDX21, DDX41 ATG7 4851/4885
US-20060292589-A1 Oligonucleotide probes containing two labels useful in hybridization assays DCLRE1B, DDX21, DCLRE1A ATG7 4685/4885
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression DCLRE1B, SNRPE, ZFR ATG7 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.