Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321538 | 0.82 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHTT | |
| SCHEMBL5325354 | 0.81 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL5328476 | 0.81 | KMT2A (0.38) | L3MBTL1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL5325901 | 0.81 | KMT2A (0.38) | L3MBTL1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL5323891 | 0.78 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL5323320 | 0.77 | MAPT (0.50) | L3MBTL1ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL5329373 | 0.77 | MAPT (0.50) | L3MBTL1ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL34472997 | 0.77 | TDP1 (0.43) | ALDH1A1KDM4EHPGDGAACYP3A4 | |
| SCHEMBL14397187 | 0.73 | PTGES (0.39) | L3MBTL1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL633461 | 0.72 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1KDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121416-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |